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  1 - The Effect of Aerobic and Nonlinear Resistance Training on Inflammatory Factors and its Relationship with Pain and Function in Overweight Women with Osteoarthritis of the Knee
  Zahra Koohestani Sini Kohanpour Mohammad-Ali Zohreh  Ghafouri Hamide  Nakhayi
  the aim of this study was to compare the effect of aerobic and nonlinear resistance training on inflammatory factors and its relationship with pain and function in overweight women with osteoarthritis of the knee. 21 women aged 50 to 60 years with knee osteoarthritis we More

  the aim of this study was to compare the effect of aerobic and nonlinear resistance training on inflammatory factors and its relationship with pain and function in overweight women with osteoarthritis of the knee. 21 women aged 50 to 60 years with knee osteoarthritis were randomly divided into three groups of aerobic exercise, nonlinear resistance training and control (7 people in each group). Exercises were performed for12 weeks (3 sessions per week). Before and after the training period, the subjects were measured for pain and motor function and blood samples were taken from three groups after the 12-hour fasting period and levels of CRP and TNF-α were measured for each sample. Both types of exercises significantly reduced weight, BMI, pain and TNF-α and CRP levels and significantly improved motor function in women with osteoarthritis of the knee (P<0.05), but no significant difference was observed between the two types of exercise (P>0.05). Also, with decreasing inflammation, pain decreased and motor function increased (P<0.05). Training with weight loss and inflammatory factors in overweight women with osteoarthritis of the knee can reduce pain and improve motor function in these women. There is probably no significant difference between the effect of aerobic and nonlinear resistance training in this area. Manuscript profile
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  2 - The Effect of Saffron Supplementation with Aerobic Training on Inflammatory Factors and Cognitive Status in Elderly Men
  Sara Naeimi Zahra  Koohestani Sini Mohammad-Ali Kohanpour Hamide  Nakhayi
  the aim of this study was to evaluate the effect of 12 weeks of aerobic training and saffron supplementation on cognitive status and serum levels of IL-1β and TNF-α in elderly men. Forty men aged 60 to 70 years were purposefully selected and randomly divided into 4 gro More

  the aim of this study was to evaluate the effect of 12 weeks of aerobic training and saffron supplementation on cognitive status and serum levels of IL-1β and TNF-α in elderly men. Forty men aged 60 to 70 years were purposefully selected and randomly divided into 4 groups: aerobic training, saffron, aerobic training + saffron and placebo (10 people in each group). Interventions were performed for 12 weeks. Aerobictraining consisted of eight minutes of running with an intensity of 75 to 85% of the maximum reserve heart rate in the first session. Both sessions increased the running time by one minute until after 12 weeks, the running time reached 26 minutes. Saffron extract was taken as a capsule with a dose of 500 mg in two meals in the morning and after exercise. IL-1β and TNF-α levels were significantly reduced in both training and saffron groups, but in the training + saffron group, their decrease was greater (P<0.05). Cognitive status in the three intervention groups increased significantly compared to the placebo group, which was higher in the exercise + saffron group (P<0.05). It is possible that taking saffron supplement along with aerobic training for 12 weeks, by improving the cognitive status in older men by reducing inflammatory factors, can prevent cognitive disorders and eventually Alzheimer's. Manuscript profile