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  1 - The Effect of Saffron Supplementation with Aerobic Training on Inflammatory Factors and Cognitive Status in Elderly Men
  Sara Naeimi Zahra  Koohestani Sini Mohammad-Ali Kohanpour Hamide  Nakhayi
  the aim of this study was to evaluate the effect of 12 weeks of aerobic training and saffron supplementation on cognitive status and serum levels of IL-1β and TNF-α in elderly men. Forty men aged 60 to 70 years were purposefully selected and randomly divided into 4 gro More

  the aim of this study was to evaluate the effect of 12 weeks of aerobic training and saffron supplementation on cognitive status and serum levels of IL-1β and TNF-α in elderly men. Forty men aged 60 to 70 years were purposefully selected and randomly divided into 4 groups: aerobic training, saffron, aerobic training + saffron and placebo (10 people in each group). Interventions were performed for 12 weeks. Aerobictraining consisted of eight minutes of running with an intensity of 75 to 85% of the maximum reserve heart rate in the first session. Both sessions increased the running time by one minute until after 12 weeks, the running time reached 26 minutes. Saffron extract was taken as a capsule with a dose of 500 mg in two meals in the morning and after exercise. IL-1β and TNF-α levels were significantly reduced in both training and saffron groups, but in the training + saffron group, their decrease was greater (P<0.05). Cognitive status in the three intervention groups increased significantly compared to the placebo group, which was higher in the exercise + saffron group (P<0.05). It is possible that taking saffron supplement along with aerobic training for 12 weeks, by improving the cognitive status in older men by reducing inflammatory factors, can prevent cognitive disorders and eventually Alzheimer's. Manuscript profile
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  2 - The Effect of Ketogenic Diet with Resistance Training on Serum Adropin Level and Insulin Resistance in overweight women
  Niloufar Bolourian Kashi Zahra  Koohestani Sini Mahnaz  Seifi Hamideh  Nakhayi
  the aim of the present study was to evaluate the effect of eight weeks of ketogenic diet combined with resistance training on serum adropine levels and insulin resistance in overweight women. 40 women aged 30 to 40 years in Mashhad with a body mass index of more tha More

  the aim of the present study was to evaluate the effect of eight weeks of ketogenic diet combined with resistance training on serum adropine levels and insulin resistance in overweight women. 40 women aged 30 to 40 years in Mashhad with a body mass index of more than 25 but less than 30 were purposefully selected and participated in this study voluntarily. After selecting the subjects, they were randomly divided into four groups: resistance training, ketogenic diet, resistance training + ketogenic diet and control (10 people in each group). Interventions were applied for four weeks. The results showed that only the effect of diet on weight loss, BMI, WHR, fat percentage and body fat mass was significant (P <0.05) but the effect of exercise and the interactive effect of exercise and diet were not significant (P> 0.05). Also, the results showed that the effect of exercise and the interactive effect of exercise and diet on reducing glucose, insulin and insulin resistance were significant (P <0.05) but the effect of diet was not significant (P> 0.05). Finally, the results showed that the effect of exercise and the interactive effect of exercise and diet on increasing adropin was significant (P <0.05) but the effect of diet was not significant (P> 0.05). A four-week ketogenic diet will probably improve the body composition of overweight women. Meanwhile, resistance training without changing weight and body fat seems to increase adropine and improve insulin resistance. Manuscript profile